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Systemic corticosteroids for the treatment of COVID-19: Equity-related analyses and update on evidence.


ABSTRACT:

SUBMITTER: Wagner C 

PROVIDER: S-EPMC9670242 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature

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Systemic corticosteroids for the treatment of COVID-19: Equity-related analyses and update on evidence.

Wagner Carina C   Griesel Mirko M   Mikolajewska Agata A   Metzendorf Maria-Inti MI   Fischer Anna-Lena AL   Stegemann Miriam M   Spagl Manuel M   Nair Avinash Anil AA   Daniel Jefferson J   Fichtner Falk F   Skoetz Nicole N  

The Cochrane database of systematic reviews 20221117


<h4>Background</h4>Systemic corticosteroids are used to treat people with COVID-19 because they counter hyper-inflammation. Existing evidence syntheses suggest a slight benefit on mortality. Nonetheless, size of effect, optimal therapy regimen, and selection of patients who are likely to benefit most are factors that remain to be evaluated.<h4>Objectives</h4>To assess whether and at which doses systemic corticosteroids are effective and safe in the treatment of people with COVID-19, to explore e  ...[more]

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