Ontology highlight
ABSTRACT:
SUBMITTER: Wagner C
PROVIDER: S-EPMC9670242 | biostudies-literature | 2022 Nov
REPOSITORIES: biostudies-literature
Wagner Carina C Griesel Mirko M Mikolajewska Agata A Metzendorf Maria-Inti MI Fischer Anna-Lena AL Stegemann Miriam M Spagl Manuel M Nair Avinash Anil AA Daniel Jefferson J Fichtner Falk F Skoetz Nicole N
The Cochrane database of systematic reviews 20221117
<h4>Background</h4>Systemic corticosteroids are used to treat people with COVID-19 because they counter hyper-inflammation. Existing evidence syntheses suggest a slight benefit on mortality. Nonetheless, size of effect, optimal therapy regimen, and selection of patients who are likely to benefit most are factors that remain to be evaluated.<h4>Objectives</h4>To assess whether and at which doses systemic corticosteroids are effective and safe in the treatment of people with COVID-19, to explore e ...[more]