From nanoparticles to crystals: one-pot programmable biosynthesis of photothermal gold structures and their use for biomedical applications.

ABSTRACT: Inspired by nature, green chemistry uses various biomolecules, such as proteins, as reducing agents to synthesize metallic nanostructures. This methodology provides an alternative route to conventional harsh synthetic processes, which include polluting chemicals. Tuning the resulting nanostructure properties, such as their size and shape, is challenging as the exact mechanism involved in their formation is still not well understood. This work reports a well-controlled method to program gold nanostructures' shape, size, and aggregation state using only one protein type, mucin, as a reduction and capping material in a one-pot bio-assisted reaction. Using mucin as a gold reduction template while varying its tertiary structure via the pH of the synthesis, we demonstrate that spherical, coral-s

SUBMITTER: Nudelman R 

PROVIDER: S-EPMC9670439 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature