Risk factors and outcomes associated with persistent vancomycin resistant Enterococcal Bacteremia.

ABSTRACT:

Background

Prior studies have identified that vancomycin resistant enterococcus (VRE) bacteremia that persists for four days or more is an independent predictor of mortality. Despite this, there is no published data to identify those patients at highest risk of developing persistent VRE bacteremia.

Methods

This was a single center, retrospective, case-control study of adult patients with a VRE bloodstream infection (BSI). Case patients were those with persistent bacteremia (≥ 4 days despite VRE-directed therapy) and control patients were those with non-persistent bacteremia. Logistic regression was used to assess risk factors associated with persistent VRE BSIs. Secondary outcomes included in-hospital mortality, recurrent bacteremia, and breakthrough bacteremia.

Results</

SUBMITTER: Fox E 

PROVIDER: S-EPMC9670444 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature