Ontology highlight
ABSTRACT:
SUBMITTER: Kassem II
PROVIDER: S-EPMC9670951 | biostudies-literature | 2022 Nov
REPOSITORIES: biostudies-literature

Antibodies (Basel, Switzerland) 20230722 3
Autoimmune thyroid disease (AITD) refers to a spectrum of various diseases, with two extremes of clinical presentation, hypothyroidism (Hashimoto's thyroiditis (HT) and hyperthyroidism (Graves-Basedow disease (GBD)). Both conditions are characterized by presenting a cellular and humoral autoimmune reaction, with an increase in the synthesis and secretion of antibodies directed toward various thyroid antigens, together with a phenomenon of thyrocyte necrosis and apoptosis (in HT) and a persistent ...[more]