Does mechanical dyssynchrony in addition to QRS area ensure sustained response to cardiac resynchronization therapy?

ABSTRACT:

Aims

Judicious patient selection for cardiac resynchronization therapy (CRT) may further enhance treatment response. Progress has been made by using improved markers of electrical dyssynchrony and mechanical discoordination, using QRSAREA, and systolic rebound stretch of the septum (SRSsept) or systolic stretch index (SSI), respectively. To date, the relation between these measurements has not yet been investigated.

Methods and results

A total of 240 CRT patients were prospectively enrolled from six centres. Patients underwent standard 12-lead electrocardiography, and echocardiography, at baseline, 6-month, and 12-month follow-up. QRSAREA was derived using vectorcardiography, and SRSsept and SSI were measured using strain-analysis. Reverse remodelling was measured as the rel

SUBMITTER: Wouters PC 

PROVIDER: S-EPMC9671288 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature