A three-dimensional atlas of child's cardiac anatomy and the unique morphological alterations associated with obesity.

ABSTRACT:

Aims

Statistical shape models (SSMs) of cardiac anatomy provide a new approach for analysis of cardiac anatomy. In adults, specific cardiac morphologies associate with cardiovascular risk factors and early disease stages. However, the relationships between morphology and risk factors in children remain unknown. We propose an SSM of the paediatric left ventricle to describe its morphological variability, examine its relationship with biometric parameters and identify adverse anatomical remodelling associated with obesity.

Methods and results

This cohort includes 2631 children (age 10.2 ± 0.6 years), mostly Western European (68.3%) with a balanced sex distribution (51.3% girls) from Generation R study. Cardiac magnetic resonance short-axis cine scans were segmented. Three-dime

SUBMITTER: Marciniak M 

PROVIDER: S-EPMC9671403 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature