Effects of stress on neural processing of combat-related stimuli in deployed soldiers: an fMRI study.

ABSTRACT: Severe trauma exposure may lead to symptoms of both posttraumatic stress disorder and depression. Neuroanatomical theories suggest that both disorders may share imbalances in fronto-limbic circuits. Longitudinal studies are necessary to better understand the impact of a stressful life situation on potential long-term fronto-limbic imbalances. Here we investigated soldiers neural processing of combat-related stimuli versus negative affective stimuli before and after the deployment in different war zones. In the final analysis we included 104 deployed soldiers (combat group) and 36 soldiers that were not deployed (control group). Behaviorally, we found a significant group by time interaction regarding depression symptom scores with an increase in the combat group. Depressive symptoms were su

SUBMITTER: Lorenz RC 

PROVIDER: S-EPMC9671957 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature