Impacts of primary tumor location on outcomes in patients undergoing hepatectomy for colorectal liver metastasis vary according to tumor burden.

ABSTRACT:

Purpose

The purpose of this study was to verify whether the prognostic value of primary tumor location (PTL) for patients undergoing resection for colorectal liver metastasis (CRLM) is affected by tumor burden.

Methods

Patients who underwent a first curative-intent surgery for CRLM from 2006 to 2017 were enrolled. The imaging tumor burden score (TBS) was calculated as TBS² = (maximum tumor diameter in cm)² + (number of lesions)². Then, the prognostic role of PTL was assessed in different TBS zones.

Results

The patient population consisted of 524 left-sided (LS) and 118 right-sided (RS) primary tumors. The distribution of TBS in the patient cohort was: Zone1: TBS <3 [n = 161 (25.1%)], zone 2: TBS ≥3 to <7 [n = 343 (53.4%)]

SUBMITTER: Wang HW 

PROVIDER: S-EPMC9672368 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature