Primary uterine osteosarcoma arising in a leiomyoma with rapid local recurrence: A case report.

ABSTRACT:

Background

Extraskeletal osteosarcoma is an extremely rare malignant neoplasm. Literature regarding primary osteosarcoma of the uterus is confined to only a small number of case reports. Case: A 57-year-old female with a history of uterine fibroids presented to the emergency department with abdominal pain. Imaging was notable for an enlarged uterus with a 15 cm calcified fibroid extending along the posterior uterus. The patient underwent a laparotomy for total hysterectomy and bilateral salpingo-oophorectomy. Pathological evaluation of the specimen yielded mesenchymal proliferation with osteoid formation and tumor cells with densely eosinophilic cytoplasm resembling osteoblasts with a final diagnosis of primary uterine osteosarcoma. Multidisciplinary tumor board recom

SUBMITTER: Ruhotina M 

PROVIDER: S-EPMC9672400 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature