Curcumin loaded Ag-TiO₂-halloysite nanotubes platform for combined chemo-photodynamic therapy treatment of cancer cells.

ABSTRACT: The use of naturally occurring anticancer materials in combination with doped metal oxide has emerged as one of the most promising ways for improving anticancer treatment efficacy. In this study, the anticancer potential of curcumin-loaded Ag-TiO₂-halloysite nanotubes (curcumin-loaded Ag-TiO₂-HNTs) was examined. Ag-TiO₂-HNTs with different wt% of Ag-TiO₂ were synthesized and characterized using XRD, TGA, FT-IR, UV-Vis spectroscopy, and SEM-EDX. The XRD results revealed the presence of crystalline TiO₂. However, the presence of Ag was detected through the SEM-EDX analysis. Cyclic voltammetry measurements suggested the enhancement of the release of ROS from TiO₂ upon deposition with Ag. FT-IR and TGA analysis confirmed the suc

SUBMITTER: Nyankson E 

PROVIDER: S-EPMC9672909 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature