Association of Cumulative Viral Load With the Incidence of Hypertension and Diabetes in People With HIV.

ABSTRACT:

Background

HIV induces several metabolic derangements that contribute to cardiovascular disease, but it is unclear if HIV increases diabetes or hypertension risk. Refining longitudinal relationships between HIV-specific factors and cardiovascular disease risk factors across different care settings may help inform cardiovascular disease prevention among people with HIV (PWH).

Methods

We tested the hypothesis that long-term higher cumulative viral load (viremia-copy-year) is associated with higher risk of diabetes and hypertension by analyzing electronic records of PWH from 2 distinct health systems in Chicago (Northwestern Medicine and Howard Brown Health Care) receiving care in 2004 to 2019. We used joint longitudinal-survival models to assess multivariable-adjusted associat

SUBMITTER: Rivera AS 

PROVIDER: S-EPMC9673163 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature