Use of antibiotics and risk of type 2 diabetes, overweight and obesity: the Cardiovascular Risk in Young Finns Study and the national FINRISK study.

ABSTRACT:

Purpose

To investigate whether exposure to systemic antibiotics influences the risk of developing type 2 diabetes and overweight/obesity.

Methods

The study sample comprised 2209 (110 with incident diabetes) participants from the population-based Cardiovascular Risk in Young Finns Study (YFS) aged 24-39 years in 2001. The exposure was national linked register data on purchased antibiotic courses between 1993 and 2001. Clinical examinations including BMI were conducted in 2001, 2007 and 2011. Participants with prevalent diabetes in 2001 were excluded. Data on type 2 diabetes was also obtained from two national registers until 2017. Data from four population-based National FINRISK studies were used for replication (N = 24,674, 1866 with incident diabetes).

Results

Prior

SUBMITTER: Nuotio J 

PROVIDER: S-EPMC9673285 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature