Comparison of Bolus Dosing of Methohexital and Propofol in Elective Direct Current Cardioversion.

ABSTRACT: Background Methohexital and propofol can both be used as sedation for direct current cardioversion (DCCV). However, there are limited data comparing these medications in this setting. We hypothesized that patients receiving methohexital for elective DCCV would be sedated more quickly, recover from sedation faster, and experience less adverse effects. Methods and Results This was a prospective, blinded randomized controlled trial conducted at a single academic medical center. Eligible participants were randomly assigned to receive either methohexital (0.5 mg/kg) or propofol (0.8 mg/kg) as a bolus for elective DCCV. The times from bolus of the medication to achieving a Ramsay Sedation Scale score of 5 to 6, first shock, eyes opening on command, and when the patient could state their age and

SUBMITTER: Beaty EH 

PROVIDER: S-EPMC9673741 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature