Low-valent tungsten redox catalysis enables controlled isomerization and carbonylative functionalization of alkenes.

ABSTRACT: The controlled isomerization and functionalization of alkenes is a cornerstone achievement in organometallic catalysis that is now widely used throughout industry. In particular, the addition of CO and H₂ to an alkene, also known as the oxo-process, is used in the production of linear aldehydes from crude alkene feedstocks. In these catalytic reactions, isomerization is governed by thermodynamics, giving rise to functionalization at the most stable alkylmetal species. Despite the ubiquitous industrial applications of tandem alkene isomerization/functionalization reactions, selective functionalization at internal positions has remained largely unexplored. Here we report that the simple W(0) precatalyst W(CO)₆ catalyses the isomerization of alkenes to unactivated intern

SUBMITTER: Jankins TC 

PROVIDER: S-EPMC9674112 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature