Association of prenatal exposure to ambient air pollution with adverse birth outcomes and effect modification by socioeconomic factors.

ABSTRACT:

Background

Maternal exposure to air pollution has been associated with birth outcomes; however, few studies examined biologically critical exposure windows shorter than trimesters or potential effect modifiers.

Objectives

To examine associations of prenatal fine particulate matter (PM_2.5), by trimester and in biologically critical windows, with birth outcomes and assess potential effect modifiers.

Methods

This study used two pregnancy cohorts (CANDLE and TIDES; N = 2099) in the ECHO PATHWAYS Consortium. PM_2.5 was estimated at the maternal residence using a fine-scale spatiotemporal model, averaged over pregnancy, trimesters, and critical windows (0-2 weeks, 10-12 weeks, and last month of pregnancy). Outcomes were preterm birth (PTB, <37 completed

SUBMITTER: Quraishi SM 

PROVIDER: S-EPMC9674115 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature