Low thoracic skeletal muscle index is associated with negative outcomes in 244 patients with respiratory COVID-19.

ABSTRACT:

Background

Sarcopenia is associated with negative outcomes in intensive care unit (ICU) patients and during chronic diseases. We aimed to evaluate if low skeletal muscle index (SMI) measured by computed tomography (CT) at the thoracic level is associated with poor outcomes in hospitalized patients with respiratory COVID-19.

Methods

Patients admitted to the hospital between March 1st and June 9, 2020 with a confirmed diagnosis of respiratory COVID-19 in the Emergency Department were included in this retrospective cohort study. SMI was assessed from a transverse CT image at the T12 level. We analysed the association between thoracic SMI and mortality, ICU admissions, infections, length of stay and gravity scores.

Results

We included 244 patients, whose median age was 62

SUBMITTER: Grigioni S 

PROVIDER: S-EPMC9674398 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature