Single-Cell Gene Expression Analysis in Patients with Medullary Sponge Kidney and a Retrospective Study.

ABSTRACT:

Objective

To establish better diagnosis thinking and provide advanced understanding of MSK, the CT imaging features, clinical characteristics, and the expression of suspected genes in the kidney spatiotemporal immune zonation and fetal renal development were investigated.

Methods

17 patients with MSK hospitalized in our hospital were selected as our research subjects. Human Phenotype Ontology, MalaCards: The Human Disease Database, GeneCards: The Human Gene Database, Human Protein Atlas, and Single Cell Expression Atlas were used to analyze this disease.

Results

In our 17 patients, the incidence of MSK tended to be the same in male and female, and the onset age of MSK was probably 31-50 years old. The top one related disease of MSK was nephrocalcinosis and the most fr

SUBMITTER: Li M 

PROVIDER: S-EPMC9674422 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature