A blockchain-based framework to support pharmacogenetic data sharing.

ABSTRACT: The successful implementation of pharmacogenetics (PGx) into clinical practice requires patient genomic data to be shared between stakeholders in multiple settings. This creates a number of barriers to widespread adoption of PGx, including privacy concerns related to the storage and movement of identifiable genomic data. Informatic solutions that support secure and equitable data access for genomic data are therefore important to PGx. Here we propose a methodology that uses smart contracts implemented on a blockchain-based framework, PGxChain, to address this issue. The design requirements for PGxChain were identified through a systematic literature review, identifying technical challenges and barriers impeding the clinical implementation of pharmacogenomics. These requirements included se

SUBMITTER: Albalwy F 

PROVIDER: S-EPMC9674519 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature