Comparison of gastric reactance with commonly used perfusion markers in a swine hypovolemic shock model.

ABSTRACT:

Background

The gut has been hypothesized to be a protagonist tissue in multiple organ dysfunction syndrome (MODS) for the past three decades. Gastric reactance (XL) is a potential perfusion marker derived from gastric impedance spectroscopy (GIS), which is an emerging tool through which living tissue can be continuously measured to determine its pathophysiological evolution. This study aimed to compare the performance of XL [positive predictive values (PPV), negative predictive values (NPV), and area under the curve (AUC)] against commonly used perfusion markers before and during hypovolemic shock in swine subjects.

Methods

Prospective, controlled animal trial with two groups, control group (CG) N = 5 and shock (MAP ≤ 48 mmHg) group (SG) N = 16. Comparison time points were d

SUBMITTER: Godinez-Garcia MM 

PROVIDER: S-EPMC9674824 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature