A multicenter real-world evidence study in the Swiss treatment landscape of chronic myeloid leukemia.

ABSTRACT:

Background

The real-world experience of Swiss chronic myeloid leukemia (CML) patients treated with tyrosine kinase inhibitors (TKIs) is largely unknown, in particular with regard to achievement of response per European Leukemia Net (ELN) criteria and adherence to ELN recommendations.

Methods

This was a retrospective, non-interventional, multicenter chart review of patients with newly diagnosed CML who had received first-line TKI and were solely treated with TKIs between 2010 and 2015, with a minimum follow-up of 18 months, at six Swiss hospitals. Effectiveness was evaluated according to ELN 2013 milestone achievements at 3, 6, 12 and 18 months, and at last follow-up.

Results

Data from 63 patients (56% men; median age at diagnosis 55 years) were collected (first-line i

SUBMITTER: Cantoni N 

PROVIDER: S-EPMC9675134 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature