SeSAM: software for automatic construction of order-robust linkage maps.

ABSTRACT:

Background

Genotyping and sequencing technologies produce increasingly large numbers of genetic markers with potentially high rates of missing or erroneous data. Therefore, the construction of linkage maps is more and more complex. Moreover, the size of segregating populations remains constrained by cost issues and is less and less commensurate with the numbers of SNPs available. Thus, guaranteeing a statistically robust marker order requires that maps include only a carefully selected subset of SNPs.

Results

In this context, the SeSAM software allows automatic genetic map construction using seriation and placement approaches, to produce (1) a high-robustness framework map which includes as many markers as possible while keeping the order robustness beyond a given statistica

SUBMITTER: Vidal A 

PROVIDER: S-EPMC9675223 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature