Bone mass density following developmental exposures to perfluoroalkyl substances (PFAS): a longitudinal cohort study.

ABSTRACT:

Background

Environmental exposures to industrial chemicals, including perfluoroalkyl substances (PFAS), may play a role in bone development and future risk of osteoporosis. However, as prospective evidence is limited, the role of developmental PFAS exposures in bone density changes in childhood is unclear. The objective of this study was to estimate associations between serum-PFAS concentrations measured in infancy and early childhood and areal bone mineral density (aBMD) measured at age 9 years in a birth cohort of children from the Faroe Islands.

Methods

We prospectively measured concentrations of five PFAS in cord serum and serum collected at 18 months, 5 years and 9 years, and conducted whole-body DXA scans at the 9-year clinical visit. Our study included 366 mother-chil

SUBMITTER: Blomberg A 

PROVIDER: S-EPMC9675242 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature