Physiological response to prone positioning in intubated adults with COVID-19 acute respiratory distress syndrome: a retrospective study.

ABSTRACT:

Background

COVID-19 related acute respiratory distress syndrome (ARDS) has specific characteristics compared to ARDS in other populations. Proning is recommended by analogy with other forms of ARDS, but few data are available regarding its physiological effects in this population. This study aimed to assess the effects of proning on oxygenation parameters (PaO₂/FiO₂ and alveolo-arterial gradient (Aa-gradient)), blood gas analysis, ventilatory ratio (VR), respiratory system compliance (C_RS) and estimated dead space fraction (V_D/V_T HB). We also looked for variables associated with treatment failure.

Methods

Retrospective monocentric study of intubated COVID-19 ARDS patients managed with an early intubation, low to moderate

SUBMITTER: Boffi A 

PROVIDER: S-EPMC9675268 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature