Anthropometric factors and the risk of ovarian cancer: A systematic review and meta-analysis.

ABSTRACT:

Background

Excess weight is convincingly associated with several cancers, but the association with ovarian cancer is insufficiently clarified, in particular regarding subgroups defined by menopausal status and ovarian cancer histologic type.

Aims

We carried out a comprehensive systematic review and meta-analysis of overweight and obesity in relation to ovarian cancer with focus on different subgroups.

Methods and results

We searched PubMed and Web of Science for relevant cohort and case-control studies published from inception to June 2021 in English language and using a clear definition of overweight and obesity. We combined maximally adjusted risk estimates using a random effects model. We analyzed data from 15 cohort and 26 case-control studies, including 28 471 ov

SUBMITTER: Ellwanger B 

PROVIDER: S-EPMC9675384 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature