The brain structure and function abnormalities of migraineurs: A systematic review and neuroimaging meta-analysis.

ABSTRACT:

Objectives

To quantitatively summarize the specific changes in brain structure and function in migraine patients.

Methods

A literature screening of migraine was conducted from inception to Sept 1, 2022, in PubMed, Web of Science, Cochrane Library, and Medline databases using the keyword combination of "migraine and MRI." Activation likelihood estimation (ALE) was performed to assess the differentiation of functional connectivity (FC), regional homogeneity (ReHo), and gray matter volume (GMV) of migraine patients.

Results

Eleven voxel-based morphometry (VBM) studies and 25 resting-state fMRI (rs-fMRI) studies (16 FC and 9 ReHo studies) were included in this study. ALE analysis revealed the ReHo increase in the brainstem and left thalamus, with no decreased area. Neithe

SUBMITTER: Chen ZH 

PROVIDER: S-EPMC9676357 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature