Insulin resistance in school-aged girls with overweight and obesity is strongly associated with elevated white blood cell count and absolute neutrophil count.

ABSTRACT:

Background

The primary objective of the study was to discuss the sex differences in insulin resistance-induced changes in metabolic and inflammatory markers in school-aged children with overweight and obesity.

Methods

A cross-sectional study of 800 children aged seven and twelve years was performed. Questionnaires, anthropometric data and fasting blood samples were collected.

Results

Children with overweight and obesity showed statistically significant differences in multiple metabolic and inflammatory markers compared with children with normal BMI. The correlation coefficient (r) between white blood cell count, absolute neutrophil count, fasting plasma insulin, HOMA-IR, HOMA-β, triglyceride, HDL-C, triglyceride/HDL ratio, alanine transaminase, serum uric acid,

SUBMITTER: He HM 

PROVIDER: S-EPMC9676363 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature