Comparison of seven cyclosporine A formulations for dry eye disease: A systematic review and network meta-analysis.

ABSTRACT: Background: Dry eye disease is a common ocular surface disease affecting tens of millions of people worldwide. It is characterized by an unstable tear film and increasing prevalence. Different commercial formulations of cyclosporine A for dry eye have been approved, however, it is still unclear whether the differences in formulations of these products will make a difference in clinical efficacy and safety. Methods: Randomized controlled trials of commercial cyclosporine A formulation for dry eye disease were searched in Pubmed, EMBASE, Scopus, and Cochrane controlled trials registries and Web of Science from inception till 1 December 2021. Independent literature screening, data extraction, quality evaluation, and the study in line with quality standards were analyzed by using

SUBMITTER: Gao D 

PROVIDER: S-EPMC9676501 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature