The impact of direct oral anticoagulants on viscoelastic testing - A systematic review.

ABSTRACT:

Background

In case of bleeding patients and in acute care, the assessment of residual direct oral anticoagulant (DOAC) activity is essential for evaluating the potential impact on hemostasis, especially when a timely decision on urgent surgery or intervention is required. Viscoelastic tests are crucial in a modern goal-directed coagulation management to assess patients' coagulation status. However, the role of viscoelastic test to detect and quantify residual DOAC plasma levels is controversially discussed. The aim of this review was to systematically summarize the evidence of viscoelastic tests for the assessment of residual DOAC activity.

Method

PubMed, Embase, Scopus, and the Cochrane Library were searched for original articles investigating the effect of rivaroxaban, api

SUBMITTER: Sahli SD 

PROVIDER: S-EPMC9676657 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature