Plasmodium cynomolgi in humans: current knowledge and future directions of an emerging zoonotic malaria parasite.

ABSTRACT: Plasmodium cynomolgi (Pcy), a simian malaria parasite, is a recent perfect example of emerging zoonotic transfer in human. This review summarizes the current knowledge on the epidemiology of natural Pcy infections in humans, mosquitoes and monkeys, along with its biological, clinical and drug sensitivity patterns. Knowledge gaps and further studies on Pcy in humans are also discussed. This parasite currently seems to be geographically limited in South-East Asia (SEA) with a global prevalence in human ranging from 0 to 1.4%. The Pcy infections were reported in local SEA populations and European travelers, and range from asymptomatic carriage to mild/moderate attacks with no evidence of pathognomonic clinical and laboratory patterns but with Pcy strain-shaped clinical differences. Geographic

SUBMITTER: Kojom Foko LP 

PROVIDER: S-EPMC9676733 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature