Postnatal corticosteroid use for prevention or treatment of bronchopulmonary dysplasia in England and Wales 2012-2019: a retrospective population cohort study.

ABSTRACT:

Objective

Describe the population of babies who do and do not receive postnatal corticosteroids for prevention or treatment of bronchopulmonary dysplasia (BPD).

Design

Retrospective cohort study using data held in the National Neonatal Research Database.

Setting

National Health Service neonatal units in England and Wales.

Patients

Babies born less than 32 weeks gestation and admitted to neonatal units from 1 January 2012 to 31 December 2019.

Main outcomes

Proportion of babies given postnatal corticosteroid; type of corticosteroid; age at initiation and duration, trends over time.

Secondary outcomes

Survival to discharge, treatment for retinopathy of prematurity, BPD, brain injury, severe necrotising enterocolitis, gastrointestinal perforation.

SUBMITTER: Yao S 

PROVIDER: S-EPMC9676997 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature