LAMC2 as a prognostic biomarker in human cancer: a systematic review and meta-analysis.

ABSTRACT:

Objectives

Accumulating evidence suggested that the laminin γ2 (LAMC2) expression level was upregulated in various cancers. However, the potential prognostic value of LAMC2 in cancers remains unclear. We conducted a meta-analysis to clarify the association of LAMC2 expression with prognosis.

Design

We searched Embase, Web of Science and PubMed (up to 25 November 2021) to collect all eligible studies, and meta-analysis was performed to interpret the association of LAMC2 expression with clinicopathological parameters, overall survival (OS), disease-specific survival (DSS) and progression-free survival (PFS).

Eligibility criteria for including studies

We included studies that investigate the relationship between LAMC2 and prognosis of cancers, patients were divided into

SUBMITTER: Fu T 

PROVIDER: S-EPMC9677043 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature