Cerebrolysin induces hair repigmentation associated to MART-1/Melan-A reactivation.

ABSTRACT: Hair graying, a prototypical sign of human aging, is a progressive loss of pigmentation from growing hair shafts caused by disease and as a side effect of medications. Cerebrolysin is a neuropeptide preparation that mimics the effect of endogenous neurotrophic factors. Cerebrolysin has been widely used in neurologic conditions, such as cerebral stroke, Alzheimer's disease, and dementia, among others. Cerebrolysin treatment has achieved to regain or maintain the cognitive ability of affected patients; however, up to date, there are no reports about the reactivation of hair pigmentation. We describe a previously not described effect occurring on patients receiving Cerebrolysin treatment for neurologic diseases and whether this effect is associated in reactivation of melanocytes and melanin e

SUBMITTER: Villarreal-Reyna G 

PROVIDER: S-EPMC9677656 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature