Gene expression profile of placentomes and clinical parameters in the cows with retained placenta.

ABSTRACT:

Background

Retained placenta (RP) is a prevalent disorder in cattle with many health-related and economic costs for the farm owners. Its etiology has not been clarified yet and there is no definite therapy for this disorder. In this study we conducted RNA-seq, hematologic and histologic experiments to survey the causes of RP development.

Methods

Blood samples were collected from 4 RP and 3 healthy cows during periparturtion period for hematological assessments followed by placentome sampling within 30 min after parturition. Cows were grouped as RP and control in case the placenta was retained or otherwise expelled, respectively. Total RNA was extracted from placentome samples followed by RNA-sequencing.

Results

We showed 240 differentially expressed genes (DEGs) betwe

SUBMITTER: Moradi M 

PROVIDER: S-EPMC9677913 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature