Age-specific prevalence and genotype distribution of human papillomavirus in women from Northwest China.

ABSTRACT:

Background

Human papillomavirus (HPV) is the leading cause of cervical cancer with more than 200 genotypes. Different genotypes have different potentials in causing premalignant lesions and cervical cancers. In this study, we investigated the age-specific prevalence and genotype distribution of HPV genotypes in Northwest China.

Materials and methods

We recruited 145,918 unvaccinated women from Northwest China for population-based HPV DNA screening test during June 2015 to December 2020. And a lab-based test was performed for each volunteer by flow fluorescent technology to identify the genotypes of HPV.

Results

The overall infection rate of HPV was 22.97%. With the participants divided into 12 groups according to age, a bimodal curve of infection rate was obtained. An

SUBMITTER: Lin X 

PROVIDER: S-EPMC9678107 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature