No associations between C-reactive protein and spinal pain trajectories in children and adolescents (CHAMPS study-DK).

ABSTRACT: Preliminary evidence points to a link between C-reactive protein (CRP) and spinal pain in adults. However, there is a paucity of research in younger populations. Therefore, we aimed to determine associations between CRP and spinal pain in childhood and adolescence. We identified trajectories of spinal pain from childhood to adolescence and investigated the associations between CRP and trajectory subgroups. Six- to 11-year-old children from 13 primary schools, were followed from October 2008 and until 2014. High-sensitivity CRP collected at baseline (2008) was measured using serum samples. The outcome was the number of weeks with non-traumatic spinal pain between November 2008 and June 2014. We constructed a trajectory model to identify different spinal pain trajectory subgroups. The associ

SUBMITTER: Beynon AM 

PROVIDER: S-EPMC9678870 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature