Developing a new sepsis screening tool based on lymphocyte count, international normalized ratio and procalcitonin (LIP score).

ABSTRACT: Exploring an effective sepsis screening tool that can be widely implemented is important for improving the prognosis of sepsis worldwide. This study aimed to develop a new simple screening tool for sepsis (LIP scoring system) that includes the peripheral blood lymphocyte count, international normalized ratio, and procalcitonin level. In a single-center, prospective, observational study, 444 acute sepsis inpatients and 444 nonsepsis inpatients were ultimately included based on the Sepsis-3 and exclusion criteria. The differences in the Lym, INR, PCT level and other clinical biomarkers were compared between the two groups. Univariable and multivariable logistic regression analyses and receiver operating characteristic analysis were used to establish a LIP screening tool for sepsis with a com

SUBMITTER: Liu B 

PROVIDER: S-EPMC9678875 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature