Global, regional and national estimates of influenza-attributable ischemic heart disease mortality.

ABSTRACT:

Background

Influenza virus infection is associated with incident ischemic heart disease (IHD) events. Here, we estimate the global, regional, and national IHD mortality burden attributable to influenza.

Methods

We used vital registration data from deaths in adults ≥50 years (13.2 million IHD deaths as underlying cause) to assess the relationship between influenza activity and IHD mortality in a non-linear meta-regression framework from 2010 to 2019. This derived relationship was then used to estimate the global influenza attributable IHD mortality. We estimated the population attributable fraction (PAF) of influenza for IHD deaths based on the relative risk associated with a given level of weekly influenza test positivity rate and multiplied PAFs by IHD mortality from the Gl

SUBMITTER: Chaves SS 

PROVIDER: S-EPMC9678904 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature