Lithium doped biphasic calcium phosphate: Structural analysis and osteo/odontogenic potential in vitro.

ABSTRACT: Biphasic calcium phosphate (BCP) is generally considered a good synthetic bone graft material with osteoinductive potential. Lithium ions are trace elements that play a role in the bone-remodeling process. This study aimed to investigate the effects of lithium ions on the phase, crystal structure, and biological responses of lithium doped BCPs and to identify improvements in their osteogenic properties. Lithium-doped BCP powders with different doping levels (0, 5, 10, and 20 at%) were synthesized via the co-precipitation method. We found that the four types of lithium-doped BCP powders showed different phase compositions of hydroxyapatite and β-tricalcium phosphate. In addition, lithium ions favored entering the β-tricalcium phosphate structure at the Ca (4) sites and calcium vacanc

SUBMITTER: Yoo KH 

PROVIDER: S-EPMC9679216 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature