The effects of exploratory behavior on physical activity in a common animal model of human disease, zebrafish (Danio rerio).

ABSTRACT: Zebrafish (Danio rerio) are widely accepted as a multidisciplinary vertebrate model for neurobehavioral and clinical studies, and more recently have become established as a model for exercise physiology and behavior. Individual differences in activity level (e.g., exploration) have been characterized in zebrafish, however, how different levels of exploration correspond to differences in motivation to engage in swimming behavior has not yet been explored. We screened individual zebrafish in two tests of exploration: the open field and novel tank diving tests. The fish were then exposed to a tank in which they could choose to enter a compartment with a flow of water (as a means of testing voluntary motivation to exercise). After a 2-day habituation period, behavioral observations were

SUBMITTER: DePasquale C 

PROVIDER: S-EPMC9679429 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature