Association between trajectories of fasting plasma glucose and risk of osteoporosis in non-diabetic and diabetic populations.

ABSTRACT:

Introduction

Previous studies based on a single measure of fasting plasma glucose (FPG) showed an inconsistent conclusion about the association between FPG and osteoporosis risk. Not accounting for time-varying and cumulative average of FPG over time could bias the true relation between FPG and osteoporosis. Our study aims to investigate the association between the trajectories of FPG and osteoporosis risk for non-diabetic and diabetic populations.

Methods

A total of 18,313 participants who attended physical examinations during 2008-2018 were included. They were free of osteoporosis at their first physical examination and followed until their last physical examination before December 31, 2018. We recorded their incidence of osteoporosis and at least three FPG values during f

SUBMITTER: Wang P 

PROVIDER: S-EPMC9679646 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature