Preparation of triangular silver nanoparticles and their biological effects in the treatment of ovarian cancer.

ABSTRACT:

Background

In recent years, silver nanoparticles (AgNPs) have gradually been widely used, especially in the field of anticancer medicine. Ovarian cancer (OC) is the gynaecological malignancy with the highest mortality rate, and the current treatment is still based on surgery, chemotherapy and postoperative targeted therapy. Therefore, the development of safe and effective nanoparticles for targeted therapy of OC is very important. This study aimed to prepare a new type of triangular silver nanoparticles (tAgNPs) and evaluate the anticancer properties for OC in vitro and in vivo.

Methods

The tAgNPs were chemically synthesized and characterized using scanning electron microscopy (SEM), ultraviolet (UV) spectrophotometry and other techniques. By performing cell-based tests, suc

SUBMITTER: Yin M 

PROVIDER: S-EPMC9680130 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature