Effect on Cellular Vitality In Vitro of Novel APRF-Chlorhexidine Treated Membranes.

ABSTRACT:

Introduction

Chlorhexidine (CHX) has been used for some time in clinical practice as a local antiseptic agent with excellent efficacy. The combination of CHX with APRF (Advanced-platelet rich fibrin) membrane has the potential to stimulate tissue regeneration and to provide a bactericidal effect. We hypothesize that this may reduce the rate of infections development and protect cell viability.

Aim

The aim of this study was two-fold-to create a stable APRF membrane treated with different concentrations of CHX (0.01% and 0.02%) and to monitor its effect on the viability of PDL cells in vitro. This benefits the introduction of a new protocol for APRF membrane production -CHX-PRF and enriches the available evidence on the effect of this antiseptic agent on PDL (Periodontal ligam

SUBMITTER: Gavrailov T 

PROVIDER: S-EPMC9680238 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature