Application of pseudocontinuous arterial spin labeling perfusion imaging in children with autism spectrum disorders.

ABSTRACT:

Introduction

Pseudocontinuous Arterial Spin Labeling (pCASL) perfusion imaging allows non-invasive quantification of regional cerebral blood flow (CBF) as part of a multimodal magnetic resonance imaging (MRI) protocol. This study aimed to compare regional CBF in autism spectrum disorders (ASD) individuals with their age-matched typically developing (TD) children using pCASL perfusion imaging.

Materials and methods

This cross-sectional study enrolled 17 individuals with ASD and 13 TD children. All participants underwent pCASL examination on a 3.0 T MRI scanner. Children in two groups were assessed for clinical characteristics and developmental profiles using Autism Behavior Checklist (ABC) and Gesell development diagnosis scale (GDDS), respectively. We compared CBF in differe

SUBMITTER: Ye F 

PROVIDER: S-EPMC9680558 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature