Unbiased retrieval of frequency-dependent mechanical properties from noisy time-dependent signals.

ABSTRACT: The mechanical response of materials to dynamic loading is often quantified by the frequency-dependent complex modulus. Probing materials directly in the frequency domain faces technical challenges such as a limited range of frequencies, long measurement times, or small sample sizes. Furthermore, many biological samples, such as cells or tissues, can change their properties upon repetitive probing at different frequencies. Therefore, it is common practice to extract the material properties by fitting predefined mechanical models to measurements performed in the time domain. This practice, however, precludes the probing of unique and yet unexplored material properties. In this report, we demonstrate that the frequency-dependent complex modulus can be robustly retrieved in a model-independen

SUBMITTER: Abuhattum S 

PROVIDER: S-EPMC9680806 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature