Evidence-Based Approach to the Surgical Management of Acute Pancreatitis.

ABSTRACT: Background  Acute pancreatitis is a significant challenge to health services. Remarkable progress has been made in the last decade in optimizing its management. Methods  This review is a comprehensive assessment of 7 guidelines employed in current clinical practice with an appraisal of the underlying evidence, including 15 meta-analyses/systematic reviews, 16 randomized controlled trials, and 31 cohort studies. Results  Key tenets of early management of acute pancreatitis include severity stratification based on the degree of organ failure and early goal-directed fluid resuscitation. Rigorous determination of etiology reduces the risk of recurrence. Early enteral nutrition and consideration of epidural analgesia have been pioneered in recent years with promising result

SUBMITTER: Sagar AJ 

PROVIDER: S-EPMC9681540 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature