Establishment of primary cystic echinococcosis in laboratory mice: our results in the Balb/c strain.

ABSTRACT:

Background

Establishment of experimental cystic echinococcosis (CE) in laboratory mice is required for the study of CE. Experimental CE may be established in primary or secondary forms; however, the primary form is more reliable for the study of CE.

Aims

The aim of the study was to assess the possibility of establishment of primary CE in Balb/c mice via the oral administration of Echinococcus granulosus s.l. eggs.

Methods

E. granulosus s.s. eggs were obtained from the gravid segments of the adult worms collected from an experimentally infected dog. Thirty-four female Balb/c mice were allocated into 4 groups and were orally infected with E. granulosus s.s. eggs as follows: 1) the mice with normal immunity, a single dose of 1000 eggs, 2) the

SUBMITTER: Sohraby SA 

PROVIDER: S-EPMC9681980 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature