Clinicopathological characteristics and outcome predictors of anti-glomerular basement membrane glomerulonephritis.

ABSTRACT:

Objective

To explore the clinicopathological features of anti-glomerular basement membrane (anti-GBM) glomerulonephritis (anti-GBM-GN) and the prognostic values of clinical and laboratory indicators at diagnosis on renal and patient survival.

Methods

A total of 76 patients (34 males and 42 females) with anti-GBM-GN who were hospitalized in the First Affiliated Hospital of Nanjing Medical University between January 2010 and June 2021 were included in this study. The baseline clinical features, histopathological data from renal biopsies, and predictors of renal and patient survival were retrospectively analyzed.

Results

Among the 76 patients, the median serum creatinine at diagnosis was 618.0 (350.98, 888.25) μmol/L and the median estimated glomerular filtration rate (e

SUBMITTER: Ge Y 

PROVIDER: S-EPMC9683053 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature