Characterization of pregnancy outcome of women with an offspring with inborn errors of metabolism: A population-based study.

ABSTRACT: Introduction: Inborn errors of metabolism (IEM) are scarce, and their diagnosis is often made after birth. This has led to the perception that most fetuses affected by these disorders do not become clinically apparent during pregnancy. Our aim was to determine the obstetrical characteristics of women with an offspring affected by IEM. Methods: This population-based retrospective cohort study included all women who delivered at the Soroka University Medical Center (SUMC) from 1988 to 2017 who met the inclusion criteria. Mothers who had an offspring with IEM were included in the study group, and those who had offsprings without IEM comprised the comparison group. Results: A total of 388,813 pregnancies were included in the study, and 184 of them were complicated b

SUBMITTER: Epstein Weiss T 

PROVIDER: S-EPMC9683332 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature