Probiotics for constipation in Parkinson's: A systematic review and meta-analysis of randomized controlled trials.

ABSTRACT:

Background

Parkinson's disease (PD)-related constipation may affects both disease occurrence and disease progression. Probiotics, as a potential therapeutic intervention, have attracted the attention of researchers, but the evidence of their efficacy and safety has not been systematically reviewed.

Aim

A systematic review and meta-analysis of randomized controlled trials of probiotics in the treatment of PD constipation was conducted to determine the efficacy and safety of probiotics in the treatment of PD constipation.

Methods

Four databases (The Cochrane Central Register of Controlled Trials, Embase, PubMed, and Web of Science) were searched from their establishment to June 1, 2022. We included randomized controlled trials of probiotics for the treatment of constipa

SUBMITTER: Yin S 

PROVIDER: S-EPMC9684193 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature