Perivascular fat attenuation for predicting adverse cardiac events in stable patients undergoing invasive coronary angiography.

ABSTRACT:

Background

Inflammation surrounding the coronary arteries can be non-invasively assessed using pericoronary adipose tissue attenuation (PCAT). While PCAT holds promise for further risk stratification of patients with low coronary artery disease (CAD) prevalence, its value in higher risk populations remains unknown.

Methods

CORE320 enrolled patients referred for invasive coronary angiography with known or suspected CAD. Coronary computed tomography angiography (CCTA) images were collected for 381 patients for whom clinical outcomes were assessed 5 years after enrollment. Using semi-automated image analysis software, PCAT was obtained and normalized for the right coronary (RCA), left anterior descending (LAD), and left circumflex arteries (LCx). The association between PCAT an

SUBMITTER: Chatterjee D 

PROVIDER: S-EPMC9684349 | biostudies-literature | 2022 Nov-Dec

REPOSITORIES: biostudies-literature